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Contribution of VMA5 to vacuolar function， stress response， ion homeostasis and autophagy in Candida albicans

Future Microbiol. 2017-10; 
ZhangKai, JiaChang, YuQilin, XiaoChenpeng, DongYijie, ZhangMeng, ZhangDan, ZhaoQiang, ZhangBiao, LiMing
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Catalog Antibody … The protein was analyzed by SDS-PAGE and western blotting. Both GFP–Atg8 and GFP were detected using the GFP-antibody (Genscript, Nanjing, China), and alpha-tubulin was detected as a control. • RNA isolation & quantitative real-time PCR analysis … Get A Quote

摘要

V-ATPase is a conservative multi-subunit enzyme in eukaryotes and modulates several cellular responses. This study aimed to illustrate the roles of Vma5 in vacuolar function， oxidative stress response， calcium homeostasis， autophagy and virulence.

关键词

Candida albicans，Vma5，autophagy，calcium，filamentous，oxidative stress，virul
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