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Inhibitory effect of flavonoids against NS2B-NS3 protease of ZIKA virus and their structure activity relationship

Biotechnol. Lett.. 2017-03; 
LimHee-Jung, NguyenThi Thanh Hanh, KimNahyun M, ParkJun-Seong, JangTae-Su, KimD
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Codon Optimization … Materials and methods. Preparation of ZIKV NS2B-NS3 pro. ZIKV NS2B-NS3 pro gene was synthesized after codon optimization (Genscript, Piscataway, NJ, USA) for expression in E. coli based on amino acid sequence of NS2B-NS3 pro (GenBank Accession No … Get A Quote

摘要

To determine the inhibitory activities of flavonoids against NS2B-NS3 protease of ZIKA virus (ZIKV NS2B-NS3) expressed in Escherichia coli BL21 (DE3) and their structure activity relationship.

关键词

Flavanoids，Myricetin，Polyphenols，Protease，Zika v
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