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HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription.

Retrovirology. 2018; 
IvanovAndrey，LinXionghao，AmmosovaTatiana，IlatovskiyAndrey V，KumariNamita，LassiterHatajai，AfangbedjiNowah，NiuXiaomei，PetukhovMichael G，NekhaiSe
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摘要

HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat phosphorylation in cultured cells and its functionality.

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