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Surveillance Study of Influenza Occurrence and Immunity in a Wisconsin Cohort During the 2009 Pandemic.

Open Forum Infect Dis. 2017;

LoChia-Yun，StroblSusan L，DunhamKimberly，WangWei，StewartLucy，MisplonJulia A，GarciaMayra，GaoJin，OzawaTatsuhiko，PriceGraeme E，NavidadJose，GradusSteve，BhattacharyyaSanjib，ViboudCecile，EichelbergerMaryna C，WeissCarol D，GorskiJack，EpsteinSuzan

Products/Services Used	Details	Operation
Peptide Synthesis	The peptides for the 25 pools and pH1N1 NP418-426 variant LPFERATVM were synthesized by GenScript (Piscataway, NJ).	Get A Quote
Bacterial Expression System		Get A Quote

摘要

Antibody and T-cell immunity to conserved influenza virus antigens can protect animals against infection with diverse influenza strains. Although immunity against conserved antigens occurs in humans， whether such responses provide cross-protection in humans and could be harnessed as the basis for universal influenza vaccines is controversial. The 2009 pandemic provided an opportunity to investigate whether pre-existing cross-reactive immunity affected susceptibility to infection.