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Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs

Science Signaling. 2018; 
Heather Torrey, John Butterworth, Toshiyuki Mera, Yoshiaki Okubo, Limei Wang, Danielle Baum, Audrey Defusco, Sara Plager, Sarah Warden,Daniel Huang, Eva Vanamee, Rosemary Foster, Denise L. Faustman
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Peptide Synthesis ELISA was used for linear epitope mapping of TNFR2 antagonists on the TNFR2 external membrane protein sequence. Peptides were purchased from GenScript, diluted in coating buffer (REF), and placed on Immulon 4HBX Flat Bottom Microtiter Plates (Thermo Scientific) at a concentration of 1 mg per well. Get A Quote

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