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Protein kinase A–induced internalization of Slack channels from the neuronal membrane occurs by adaptor protein-2/clathrin–mediated endocytosis

American Society for Biochemistry and Molecular Biology. 2017;

SG conducted most of the experiments, analyzed the results and wrote the paper. KME prepared the adult mouse spinal cord slices. KDP performed the immunoflourescence analysis. JL and JQ performed the mass spectrometry experiments. AB conceived the idea for the project and supervised manuscript preparation by SG.

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Peptide Synthesis	Pharmacology- Inhibitor and Scrambled peptide compounds were custom ordered from GenScript. Following five days of culture, DRG neurons were preincubated in peptide (10 µM) for 24 hours, followed by treatment for 30 minutes with the cAMP analog SpcAMPs (50 µM) for PKA activation, at 37°C.	Get A Quote