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MiR-486-5p inhibits the proliferation of leukemia cells and induces apoptosis through targeting FOXO1.

Mol. Cell. Probes. 2019;

LiuHui，NiZengfeng，ShiLili，MaLijie，ZhaoJianq

Products/Services Used	Details	Operation
Recombinant Proteins	… secondary antibody using horseradish peroxidase-conjugated goat IgG (A0208; 1:1000; Beyotime, Suzhou, China) at room temperature for 2 h. Antibodies against cleaved caspase-3 (17 kDa) (#9661; 1:1000; CST) and GAPDH (36 kDa) (ab8245; 1:1000; GenScript, USA) were …	Get A Quote

摘要

Studies have reported that micro (miR)-486-5p plays a crucial part in the progression of leukemia， however， to the best of our knowledge， few studies have been conducted on its mechanism in leukemia. In this study， the mechanism of miR-486-5p in leukemia cells was pointed out and its possible target genes were analyzed for the purpose of providing new therapeutic strategies for treating leukemia patients.