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Tripeptide IRW initiates differentiation in osteoblasts differentiation via the RUNX2 pathway.

Biochim Biophys Acta Gen Subj. 2019; 
ShangNan，BhullarKhushwant S，HubbardBasil P，WuJian
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Peptide Synthesis … molecular mechanism(s). 2. Materials and methods. 2.1. Reagents. The tripeptide IRW was synthesized by GenScript (Piscataway, NJ, USA). Peptide sequence and purity (99.8%) was validated by HPLC-MS/MS. Minimum essential … Get A Quote

摘要

Osteoblasts maintain the structural integrity of bone via differentiation and mineralization; therefore， their malfunction or reduced activity can cause serious bone disorders. Although studies have demonstrated the association between nutrients and bone， research on food-derived bioactive peptides and bone health are scanty.

关键词

Differentiation，Osteogenesis，Osteoporosis，PI3K-Akt，RUNX2，Tripeptide
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