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Transient Down-Regulation of Nucleoside Transporter 3 Gene Expression as a Drug Target in Antisense RNA Technology.

Iran J Parasitol. 2019; 
TohidiFarideh，KazemiBahram，BandehpourMojgan，SharifiIraj，RabieiMohammad Reza，Saedi DezakiEbrahim，BabaeiZ
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Catalog Antibody … 10% acrylamide gel (19). The protein bands were transferred to a nitrocellulose membrane. NT3-specific sheep antibody was used as a primary antibody with titer of 1:1000 (Genscript, USA). Rabbit anti-sheep IgG antibody … Get A Quote

摘要

This study was aimed to silencing the Nucleoside transporter 3 (NT3) permease nucleobases involved in the salvage pathway of in order to disrupt purine nucleotide uptake in the parasite and consequently， destruction of the parasite.

关键词

Antisense RNA，Drug target，Gene expression，Leishmania major，Nucleoside transporter 3
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