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Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.

Cell. 2018; 
Rubio-CosialsAnna,SchulzEike C,LambertsenLotte,SmyshlyaevGeorgy,Rojas-CordovaCarlos,ForslundKristoffer,KaracaEzgi,BebelAleksandra,BorkPeer,BarabasOrs
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摘要

Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.,Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany; Hamburg Outstation, European Molecular Biology Laboratory, 22603 Hamburg, Germany.,Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.,Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Hinxton CB10 1SD, UK.,Structural and Computa... More

关键词

DNA complex,Tn1549 transposon,Tn916-like transposon family,antibiotic resistance,conjugative transposition,crystallography,gene transfer,multidrug-resistant bacteria,tyrosine recombinase,vancom
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