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Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria.

J. Antimicrob. Chemother.. 2019; 
HirschRolf，WiesnerJochen，MarkerAlexander，PfeiferYvonne，BauerArmin，HammannPeter E，VilcinskasAnd
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Peptide Synthesis 16,17 Antimicrobial peptides LS-sarcotoxin and LS-stomoxyn and the corresponding D-enantiomers were produced by solid-phase synthesis at 90% purity (GenScript, USA). Get A Quote

摘要

The ability of MDR Gram-negative bacteria to evade even antibiotics of last resort is a severe global challenge. The development pipeline for conventional antibiotics cannot address this issue， but antimicrobial peptides (AMPs) offer an alternative solution.

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