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Internalization， Trafficking， Intracellular Processing and Actions of Antibody-Drug Conjugates.

Pharm. Res.. 2015; 
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Recombinant Proteins cientific Development Manager, Discovery Biology, GenScript USA Inc., 860 Centennial Ave., Piscataway, New Jersey, 08854, USA Shi Xu Get A Quote

摘要

This review discusses the molecular mechanism involved in the targeting and delivery of antibody-drug conjugates (ADCs)， the new class of biopharmaceuticals mainly designed for targeted cancer therapy.

关键词

Antibody drug conjugate，Internalization，Linker，Recycling，Traffic
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