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Role of corticosteroid in the management of COVID-19: A systemic review and a Clinician's perspective

Diabetes Metab Syndr. 2020-06-01; 
Awadhesh Kumar Singh, Sujoy Majumdar, Ritu Singh, Anoop Misra
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Codon Optimization … Generation of expression constructs and inducible Flp-In™ 293 T-REx cell lines. The WT human or mouse CEBPE full length coding sequence without stop codon were commercially cloned into a Gateway®-compatible pDONR221 entry-vector (GenScript) … Get A Quote

摘要

objective: Interest in corticosteroid therapy in COVID-19 has been rekindled after the results from Randomized Evaluation of COVid-19 thERapY (RECOVERY) Trial. However, the World health Organization has not recommended corticosteroid in the treatment of COVID-19. We sought to conduct a systematic review on the role of corticosteroid in the management of patients of COVID-19. methods: A systematic electronic search of PubMed, Cochrane and MedRxiv database using specific keywords was made up till June 17, 2020. Full text of all the original articles with supplementary appendix that fulfilled the inclusion criteria were retrieved and a detailed analysis of results were represented. results: Of the 5 studies (4 ret... More

关键词

ARDS, COVID-19, Corticosteroids, Dexamethasone, Methylprednisolone, SARS-CoV-2
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