| Products/Services Used | Details | Operation |
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| Catalog Antibody | … The membranes were incubated with primary antibodies (Cell Signaling Technology, #2454; diluted 1 : 1 000) in 5% non-fat dry milk and then with secondary, HRP-conjugated goat anti-rabbit antibodies (Genscript, Piscataway, NJ, USA, A00098; diluted 1 : 10 000) … | Get A Quote |
Cranberry extract (CBE) rich in polyphenols are potent to delay paralysis induced by alleviating β-amyloid (Aβ) toxicity in C. elegans model of Alzheimer's disease (AD). In order to better apply CBE as an anti-AD agent efficiently, we sought to deterrmine whether preventive or therapeutic effect contributes more prominently toward CBE's anti-AD activity. As the level of Aβ toxicity and memory health are two major pathological parameters in AD, in the present study, we compared the effects of CBE on Aβ toxicity and memory health in the C. elegans AD model treated with preventive and therapeutic protocols. Our results revealed that CBE prominently showed the preventive efficacy, providing a basis for further ... More
