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Microsecond simulations and CD spectroscopy reveals the intrinsically disordered nature of SARS-CoV-2 Spike-C-terminal cytoplasmic tail (residues 1242-1273) in isolation

biorxiv. 2021-01; 
Prateek Kumar, Taniya Bhardwaj, Neha Garg, Rajanish Giri
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Peptide Synthesis For CD based experiments, the synthesized peptide of spike cytoplasmic region (residues 1242–1273) with purity 85.3 % was procured in lyophilized form from GenScript, USA. Chemicals and solvents i.e., 2,2,2-Trifluoroethanol (TFE) and Sodium Dodecyl Sulfate (SDS) with more than 99% of purity were purchased from Sigma-Aldrich, USA. Get A Quote

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