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Structural and dynamic heterogeneity in associative networks formed by artificially engineered protein polymers

Soft Matter. 2023-08; 
Ameya Rao, Bradley D Olsen
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摘要

This work investigates static gel structure and cooperative multi-chain motion in associative networks using a well-defined model system composed of artificial coiled-coil proteins. The combination of small-angle and ultra-small-angle neutron scattering provides evidence for three static length scales irrespective of protein gel design which are attributed to correlations arising from the blob length, inter-junction spacing, and multi-chain density fluctuations. Self-diffusion measurements using forced Rayleigh scattering demonstrate an apparent superdiffusive regime in all gels studied, reflecting a transition between distinct "slow" and "fast" diffusive species. The interconversion between the two diffusive m... More

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