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Temporal logic circuits implementation using a dual cross-inhibition mechanism based on DNA strand displacement

RSC Adv. 2023-09; 
Yuan Liu, Xiaokang Zhang, Xun Zhang, Xin Liu, Bin Wang, Qiang Zhang, Xiaopeng Wei
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Custom DNA/RNA Oligos … In the realm of theoretical research, DNA reaction networks … sequences were purchased from GenScript Biotech Co., Ltd. … All oligonucleotides were dissolved in 1× tris–acetate–EDTA–… Get A Quote

摘要

Molecular circuits crafted from DNA molecules harness the inherent programmability and biocompatibility of DNA to intelligently steer molecular machines in the execution of microscopic tasks. In comparison to combinational circuits, DNA-based temporal circuits boast supplementary capabilities, allowing them to proficiently handle the omnipresent temporal information within biochemical systems and life sciences. However, the lack of temporal mechanisms and components proficient in comprehending and processing temporal information presents challenges in advancing DNA circuits that excel in complex tasks requiring temporal control and time perception. In this study, we engineered temporal logic circuits through th... More

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