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A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells

Authors: Aoxing Cheng, Tian Xu , Weiyi You, Ting Wang, Dongming Zhang, Huimin Guo , Haiyan Zhang , Xin Pan , Yucai Wang , Liu Liu , Kaiguang Zhang , Jue Shi , Xuebiao Yao ， Jing Guo , Zhenye Yang

Journal: Nat Metab .

PubMed ID: 37349486

Doi: 10.1038/s42255-023-00832-9

Products & Services: Antibody Modification and Purification Services

Improving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach

Authors: Deniz Durmusoglu, Ibrahim Al'Abri, Zidan Li, Taufika Islam Williams, Leonard B Collins, José L Martínez, Nathan Crook

Journal: Microb Cell Fact

PubMed ID: 37287064

Doi: 10.1186/s12934-023-02117-y

Products & Services: Proteins, Expression, Isolation and Analysis

Spt6 directly interacts with Cdc73 and is required for Paf1 complex occupancy at active genes in Saccharomyces cerevisiae

Authors: Mitchell A Ellison, Sanchirmaa Namjilsuren, Margaret K Shirra, Matthew S Blacksmith, Rachel A Schusteff, Eleanor M Kerr, Fei Fang, Yufei Xiang, Yi Shi, Karen M Arndt

Journal: Nucleic Acids Res

PubMed ID: 36928138

Doi: 10.1093/nar/gkad180

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted sequencing of cancer-related genes reveals a recurrent TOP2A variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma

Authors: Bartlomiej Gielniewski, Katarzyna Poleszak, Adria-Jaume Roura, Paulina Szadkowska, Karol Jacek, Sylwia K Krol, Rafal Guzik, Paulina Wiechecka, Marta Maleszewska, Beata Kaza, Andrzej Marchel, Tomasz Czernicki, Andrzej Koziarski, Grzegorz Zielinski, Andrzej Styk, Maciej Kawecki, Cezary Szczylik, Ryszard Czepko, Mariusz Banach, Wojciech Kaspera, Wojciech Szopa, Mateusz Bujko, Bartosz Czapski, Miroslaw Zabek, Ewa Iżycka-Świeszewska, Wojciech Kloc, Pawel Nauman, Joanna Cieslewicz, Wieslawa Grajkowska, Natalia Morosini, Houtan Noushmehr, Bartosz Wojtas, Bozena Kaminska

Journal: Int J Cancer

PubMed ID: 37338006

Doi: 10.1002/ijc.34631

Products & Services: Proteins, Expression, Isolation and Analysis

Virtual screening, identification, and potential antioxidant mechanism of novel bioactive peptides during aging by a short-chain peptidomics, quantitative structure-activity relationship analysis, and molecular docking

Authors: An Du, Wei Jia

Journal: Food Res Int

PubMed ID: 37689894

Doi: 10.1016/j.foodres.2023.113129

Products & Services: Proteins, Expression, Isolation and Analysis

Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection

Authors: Manuela C Aguirre-Botero, Lawrence T Wang, Pauline Formaglio, Eduardo Aliprandini, Jean-Michel Thiberge, Arne Schön, Yevel Flores-Garcia, Shamika Mathis-Torres, Barbara J Flynn, Lais da Silva Pereira, Yann Le Duff, Mathew Hurley, Adéla Nacer, Paul W Bowyer, Fidel Zavala, Azza H Idris, Joseph R Francica, Robert A Seder, Rogerio Amino

Journal: Cell Rep

PubMed ID: 37389992

Doi: 10.1016/j.celrep.2023.112681

Products & Services: Peptide Synthesis

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

Authors: Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel Klein, Debbie D Nahas, Bob J Lucas, He Xi, Edward Murray, Daphne Y Ma, Krista Getty, Rachel Fearns

Journal: Commun Biol

PubMed ID: 37337079

Doi: 10.1038/s42003-023-04990-0

Products & Services: Codon Optimization

Near atmospheric carbon dioxide activates plant ubiquitin cross-linking

Authors: Harry G Gannon, Martin J Cann

Journal: BBA Adv

PubMed ID: 37416898

Doi: 10.1016/j.bbadva.2023.100096

Products & Services: Molecular Biology Reagents

Identification of paeoniflorin from Paeonia lactiflora pall As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice

Authors: Xiaoxia Liang, Ting Su, Pingzhou Wu, Yanting Dai, Yanmin Chen, QiQi Wang, Cheng Cao, Fenglian Chen, Qing Wang, Shuling Wang