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In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g
Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova
Journal: bioRxiv .
PubMed ID: 37292671
Doi: 10.1101/gad.350829.123
Products & Services: Gene Synthesis   
Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy
Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos
Journal: Diabetes
PubMed ID: 36821829
Doi: 10.2337/db22-0515
Products & Services: Proteins, Expression, Isolation and Analysis   
The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways
Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao
Journal: Microbiol Spectr
PubMed ID: 37154717
Doi: 10.1128/spectrum.00994-23
Products & Services: Proteins, Expression, Isolation and Analysis   
KRAS mutation-induced TOPK overexpression contributes to tumour progression in non-small cell lung cancer
Authors: Chang Cai, Shuo Yao, Yanmei Zou, Hui Lu, Xiuqiong Chen, Yali Wang, Kun Zheng, Feng Zhu, Yihua Wang, Hua Xiong, Junfei Zhu
Journal: J Cell Mol Med
PubMed ID: 37226642
Doi: 10.1111/jcmm.17640
Products & Services: Proteins, Expression, Isolation and Analysis   
Redundant actions of neuropeptides encoded by the dh-pban gene for larval color pattern formation in the oriental armyworm Mythimnaseparata
Authors: Yu Shirai, Hajime Ono, Takaaki Daimon
Journal: Insect Biochem Mol Biol
PubMed ID: 37146697
Doi: 10.1016/j.ibmb.2023.103955
Products & Services: Peptide Synthesis   
Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes
Authors: Elizabeth A Phillips, Adam D Silverman, Aric Joneja, Michael Liu, Carl Brown, Paul Carlson, Christine Coticchia, Kristen Shytle, Alex Larsen, Nadish Goyal, Vincent Cai, Jason Huang, Jennifer E Hickey, Emily Ryan, Joycelynn Acheampong, Pradeep Ramesh, James J Collins, William J Blake
Journal: Nat Biomed Eng
PubMed ID: 37142844
Doi: 10.1038/s41551-023-01028-y
Products & Services: Proteins, Expression, Isolation and Analysis   
Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis
Authors: Chia-Ming Chang, Kuang-Hua Cheng, Tsai-Yin Wei, Meng-Ping Lu, Yi-Chen Chen, Yen-Ta Lu
Journal: J Immunol
PubMed ID: 36961438
Doi: 10.4049/jimmunol.2200222
Products & Services: Proteins, Expression, Isolation and Analysis   
Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM
Authors: Jiayi Tian, Alejandro Arcadio Garcia, Patrick H Donnan, Jennifer Bridwell-Rabb
Journal: Biochemistry
PubMed ID: 37188334
Doi: 10.1021/acs.biochem.3c00150
Products & Services: Proteins, Expression, Isolation and Analysis   
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Authors: Torleif Tollefsrud Gjølberg, Jonas Aakre Wik, Hanna Johannessen, Stig Krüger, Nicola Bassi, Panagiotis F Christopoulos, Malin Bern, Stian Foss, Goran Petrovski, Morten C Moe, Guttorm Haraldsen, Johanna Hol Fosse, Bjørn Steen Skålhegg, Jan Terje Andersen, Eirik Sundlisæter
Journal: Nat Commun
PubMed ID: 37253747
Doi: 10.1038/s41467-023-38563-w
Products & Services: Proteins, Expression, Isolation and Analysis   
Small heterodimer partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation
Authors: JooYeon Jhun, Jeonghyeon Moon, Ji Ye Kwon, Keun-Hyung Cho, Seang Yoon Lee, Hyun Sik Na, Mi-La Cho, Jun-Ki Min
Journal: Cell Commun Signal
PubMed ID: 37143079
Doi: 10.1186/s12964-023-01054-y
Products & Services: Codon Optimization   
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