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HIV coinfection exacerbates HBV-induced liver fibrogenesis through a HIF-1α- and TGF-β1-dependent pathway

Authors: Min Xu , Charlotte Warner, Xiaoqiong Duan, Zhimeng Cheng, Andre J Jeyarajan, Wenting Li, Yongtao Wang , Tuo Shao , Shadi Salloum , Pei-Jer Chen , Xu Yu , Raymond T Chung , Wenyu Lin

Journal: J Hepatol

PubMed ID: 38311121

Doi: 10.1016/j.jhep.2024.01.026

Products & Services: Gene Synthesis

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD

Authors: Marian Hruska-Plochan, Vera I Wiersma, Katharina M Betz, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma , Laura De Vos, Karl Frontzek , Adriano Aguzzi, Tammaryn Lashley , Mark D Robinson, Theofanis Karayannis, Martin Mueller, Andreas Hierlemann 4, Magdalini Polymenidou 13

Journal: Nature

PubMed ID: 38355792

Doi: 10.1038/s41586-024-07042-7

Products & Services: Gene Synthesis

Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC

Authors: Anna Miścicka, Alexander G Bulakhov, Kazushige Kuroha, Alexandra Zinoviev, Christopher U T Hellen, Tatyana V Pestova

Journal: Nucleic Acids Res

PubMed ID: 38366554

Doi: 10.1093/nar/gkae087

Products & Services: Custom Vector Construction

The ETI-dependent receptor-like kinase 1 positively regulates effector-triggered immunity by stabilizing NLR-required for cell death 4 in Nicotiana benthamiana

Authors: Yujing Sun, Fan Liu, Mengzhu Zeng, Xinjie Zhang, Ying Cui, Zhaodan Chen, Lei Wang, Yuanpeng Xu, Jinbin Wu, Shengya Guo, Xian Dong, Suomeng Dong, Yan Wang, Yuanchao Wang

Journal: New Phytol

PubMed ID: 38362937

Doi: 10.1111/nph.19596

Products & Services: DNA Sequencing

DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α

Authors: Aidi Gao, Mingxia Zhang, Shuang Qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao

Journal: Cell Death Dis

PubMed ID: 38402183

Doi: 10.1038/s41419-024-06552-6

Products & Services: Proteins, Expression, Isolation and Analysis

Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia

Authors: Wonjae Sung, Min-Young Noh, Minyeop Nahm, Yong Sung Kim, Chang-Seok Ki, Young-Eun Kim, Hee-Jin Kim, Seung Hyun Kim

Journal: J Neuroinflammation

PubMed ID: 38347588

Doi: 10.1186/s12974-024-03039-1

Products & Services: Gene Synthesis

Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1

Authors: Courtney J Mycroft-West, Sahar Abdelkarim, Helen M E Duyvesteyn, Neha S Gandhi, Mark A Skidmore, Raymond J Owens, Liang Wu