β-Amyloid (25-35)

Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.

产品编号	RP10008
规格	1 mg 5 mg 大单询价
数量
价格	￥500


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产品概述

Synonyms	βAmyloid; b-Amyloid; bAmyloid; beta-Amyloid; betaAmyloid
Description	Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca²⁺ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca²⁺ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.
Cas No	131602-53-4
Sequence	{GLY}{SER}{ASN}{LYS}{GLY}{ALA}{ILE}{ILE}{GLY}{LEU}{MET}
Sequence Shortening	GSNKGAIIGLM
Molecular Formula	C₄₅H₈₁N₁₃O₁₄S₁
Molecular Weight	1060.27

产品属性

Purity	> 95%
Solubility	The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Form	Lyophilized
Storage	Store the peptide at -20°C