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β-淀粉样蛋白肽(Beta Amyloid Peptide,β-AP)

β淀粉样蛋白是一种与阿尔茨海默病(AD)有关的蛋白,其在患者大脑中堆积形成的淀粉样斑块的蛋白。β淀粉样蛋白肽通常含有39~43个氨基酸。在神经退行性疾病状态下,经β分泌酶和γ分泌酶依次酶解淀粉样前体蛋白(APP:一种100-140kDa的跨膜糖蛋白)而产生的不溶性低聚物,最终导致神经元死亡。由于β-淀粉样蛋白(Aβ40/42)在AD发病中起关键作用,因而成为AD的蛋白免疫疗法项目中研究较多的蛋白之一。

银河galaxy通过自主开发的PepPower™全自动合成平台,整合多肽固相合成技术、液相合成技术、微波合成技术和片段缩合技术,合成一系列涉及AD发病机理的β淀粉样蛋白目录多肽,秉承“用生物技术使人和自然更健康”的企业使命,致力于成为您信赖的生物科技公司。您可在线选购、即刻下单。

产品

产品编号 名称 数量 价格 操作
RP10004
β-Amyloid (1-40)
¥1100.00
 
RP10008
β-Amyloid (25-35)
¥500.00
 
RP10017
β-Amyloid (1-42), human
¥1100.00
 
RP10245
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat
¥1400.00 1 mg
 
RP10492
Neuropeptide Y, human
¥700.00 0.5 mg
 
RP10781
Ghrelin, rat
¥1900.00
 
RP10972
Cortistatin 14, human, rat
¥600.00 0.5 mg
 
RP11090
Calcitonin Gene Related Peptide (CGRP) (8-37), rat
¥900.00 0.5 mg
 
RP11095
Calcitonin Gene Related Peptide (CGRP), rat
¥1200.00 0.5 mg
 
RP11344
β-Endorphin, human
¥700.00 1 mg
 
RP20527
β-Amyloid (1-42), human
¥1100.00
 
RP30246
Biotin-β-Amyloid (1-42), human
¥750.00
 
RP30247
[Gly22]-β-Amyloid (1-42), Arctic Mutation
-
 
RP30248
5-FAM-β-Amyloid (1-42), human
¥750.00
 
RP30249
Biotin-β-Amyloid (1-40)
-
 
RP30250
[Gly22]-β-Amyloid (1-40), Arctic Mutation
-
 
RP30251
5-FAM-β-Amyloid (1-40)
-
 
有关银河galaxy定制化多肽合成服务,详情请见

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实验案例

参考文献

Hye-Jung Kim, Cha-Gyun Jung, Mark A. Jensen, Danuta Dukala, and Betty Soliven. Targeting of Myelin Protein Zero in a Spontaneous Autoimmune Polyneuropathy. J. Immunol. Dec 2008; 181(12): 8753 - 8760

Chulbul M. Ahmed, Rea Dabelic, Lilian W. Waiboci, Lindsey D. Jager, Linda L. Heron, and Howard M. Johnson. SOCS-1 Mimetics Protect Mice Against Lethal Poxvirus Infection: Identification of a Novel Endogenous Antiviral System. J. Virol. Nov 2008

Alexander Litovchick and Jack W. Szostak. Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display. PNAS. Oct 2008; 105(40): 15293 - 15298

Jung-Hye Choi, Joon T. Park, Ben Davidson, Patrice J. Morin, Ie-Ming Shih, and Tian-Li Wang. Jagged-1 and Notch3 Juxtacrine Loop Regulates Ovarian Tumor Growth and Adhesion. Cancer Res. Jul 2008; 68(14): 5716 - 5723

John M. Stafford, Fang Yu, Richard Printz, Alyssa H. Hasty, Larry L. Swift, and Kevin D. Niswender. Central Nervous System Neuropeptide Y Signaling Modulates VLDL Triglyceride Secretion. Diabetes. Jun 2008: 1482 - 1490

Oliver Soehnlein, Alma Zernecke, Einar E Eriksson, Antonio Gigliotti Rothfuchs, Christine T Pham, Heiko Herwald, Kiril Bidzhekov, Martin E Rottenberg, Christian Weber, and Lennart Lindbom. Neutrophil secretion products pave the way for inflammatory monocytes. Blood. Aug 2008; 112(4): 1461 - 1471

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