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A spacer design strategy for CRISPR-Cas12f1 with single-nucleotide polymorphism mutation resolution capability and its application in the mutations diagnosis of pathogens

Authors: Panqi Gao, Maoyi Yang, Yi Chen, Jun Yan, Miaomiao Han, Haijun Deng, Keli Qian, Jiandong Yang, Yaoqin Lu, Ling Zhou, Ailong Huang, Xiaosong Li, Wanyan Deng, Quanxin Long

Journal: J Med Virol

PubMed ID: 37855689

Doi: 10.1002/jmv.29189

Products & Services: Proteins, Expression, Isolation and Analysis

Intervention of AXL in EGFR Signaling via Phosphorylation and Stabilization of MIG6 in Non-Small Cell Lung Cancer

Authors: Ya-Yu Yang, Sheng-Chieh Lin, Jong-Ding Lay, Chun-Yu Cho, Te-Hsuan Jang, Hsiu-Ying Ku, Chih-Jung Yao, Shuang-En Chuang

Journal: Int J Mol Sci

PubMed ID: 37834326

Doi: 10.3390/ijms241914879

Products & Services: Proteins, Expression, Isolation and Analysis

VP2 residue N142 of coxsackievirus A10 is critical for the interaction with KREMEN1 receptor and neutralizing antibodies and the pathogenicity in mice

Authors: Xue Li, Zeyu Liu, Xingyu Yan, Yuan Tian, Kexin Liu, Yue Zhao, Jiang Shao, Pei Hao, Chao Zhang

Journal: PLoS Pathog

PubMed ID: 37788227

Doi: 10.1371/journal.ppat.1011662

Products & Services: Proteins, Expression, Isolation and Analysis

Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization

Authors: Rajesh P Ringe, Philippe Colin, Gabriel Ozorowski, Joel D Allen, Anila Yasmeen, Gemma E Seabright, Jeong Hyun Lee, Aleksandar Antanasijevic, Kimmo Rantalainen, Thomas Ketas, John P Moore, Andrew B Ward, Max Crispin, P J Klasse

Journal: PLoS Pathog

PubMed ID: 37903160

Doi: 10.1371/journal.ppat.1011601

Products & Services: Proteins, Expression, Isolation and Analysis

One ring closer to a closure: the crystal structure of the ES hydroxymethylbilane synthase intermediate

Authors: Helene J Bustad, Marthe S Christie, Mikko Laitaoja, Aasne K Aarsand, Aurora Martinez, Janne Jänis, Juha P Kallio

Journal: FEBS J

PubMed ID: 37863644

Doi: 10.1111/febs.16982

Products & Services: Proteins, Expression, Isolation and Analysis

Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes

Authors: Katrin Fischer, Michaela Bradlerova, Thomas Decker, Verena Supper

Journal: Sci Rep

PubMed ID: 37903831

Doi: 10.1038/s41598-023-45587-1

Products & Services: Proteins, Expression, Isolation and Analysis

Structural and dynamical changes of the Streptococcus gordonii metalloregulatory ScaR protein induced by Mn ion binding

Authors: Katarina Radman, Zoe Jelić Matošević, Dijana Žilić, Ivo Crnolatac, Nikola Bregović, Marina Kveder, Ivo Piantanida, Pedro A Fernandes, Ivana Leščić Ašler, Branimir Bertoša

Journal: Int J Biol Macromol

PubMed ID: 37866578

Doi: 10.1016/j.ijbiomac.2023.127572

Products & Services: Proteins, Expression, Isolation and Analysis

Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

Authors: Alžběta Motyčková, Luboš Voleman, Vladimíra Najdrová, Lenka Arbonová, Martin Benda, Vít Dohnálek, Natalia Janowicz, Ronald Malych, Róbert Šuťák, Thijs J G Ettema, Staffan Svärd, Courtney W Stairs, Pavel Doležal

Journal: PLoS Pathog

PubMed ID: 37792908

Doi: 10.1371/journal.ppat.1010773

Products & Services: Proteins, Expression, Isolation and Analysis

The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection

Authors: Déborah Lécuyer, Roberta Nardacci, Désirée Tannous, Emie Gutierrez-Mateyron, Aurélia Deva Nathan, Frédéric Subra, Cristina Di Primio, Paola Quaranta, Vanessa Petit, Clémence Richetta, Ali Mostefa-Kara, Franca Del Nonno, Laura Falasca, Romain Marlin, Pauline Maisonnasse, Julia Delahousse, Juliette Pascaud, Eric Deprez, Marie Naigeon, Nathalie Chaput, Angelo Paci, Véronique Saada, David Ghez, Xavier Mariette, Mario Costa, Mauro Pistello, Awatef Allouch, Olivier Delelis, Mauro Piacentini, Roger Le Grand, Jean-Luc Perfettini

Journal: Front Immunol

PubMed ID: 37920468

Doi: 10.3389/fimmu.2023.1270081

Products & Services: Proteins, Expression, Isolation and Analysis

A novel recombinant S-based subunit vaccine induces protective immunity against porcine deltacoronavirus challenge in piglets

Authors: Jizong Li, Shuqing Zhao, Baotai Zhang, Jin Huang, Qi Peng, Li Xiao, Xuesong Yuan, Rongli Guo, Jinzhu Zhou, Baochao Fan, Tao Xue, Xuejiao Zhu, Chuanmin Liu, Xing Zhu, Lili Ren, Bin Li

Journal: J Virol

PubMed ID: 37846983

Doi: 10.1128/jvi.00958-23

Products & Services: Proteins, Expression, Isolation and Analysis