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至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

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页码: 63/357 每页显示数量
Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models
Authors: Debashis Dutta, Malabendu Jana, Ramesh Kumar Paidi, Moumita Majumder, Sumita Raha, Sridevi Dasarathy, Kalipada Pahan
Journal: J Clin Invest
PubMed ID: 37552543
Doi: 10.1172/JCI161987
Unambiguous discrimination of all 20 proteinogenic amino acids and their modifications by nanopore
Authors: Kefan Wang, Shanyu Zhang, Xiao Zhou, Xian Yang, Xinyue Li, Yuqin Wang, Pingping Fan, Yunqi Xiao, Wen Sun, Panke Zhang, Wenfei Li, Shuo Huang
Journal: Nat Methods
PubMed ID: 37749214
Doi: 10.1038/s41592-023-02021-8
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo
Authors: Burcu Bestas, Sandra Wimberger, Dmitrii Degtev, Alexandra Madsen, Antje K Rottner, Fredrik Karlsson, Sergey Naumenko, Megan Callahan, Julia Liz Touza, Margherita Francescatto, Carl Ivar Möller, Lukas Badertscher, Songyuan Li, Silvia Cerboni, Niklas Selfjord, Elke Ericson, Euan Gordon, Mike Firth, Krzysztof Chylinski, Amir Taheri-Ghahfarokhi, Mohammad Bohlooly-Y, Mike Snowden, Menelaos Pangalos, Barrett Nuttall, Pinar Akcakaya, Grzegorz Sienski, Marcello Maresca
Journal: Nat Commun
PubMed ID: 37673883
Doi: 10.1038/s41467-023-41240-7
Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II
Authors: David Flores-Solis, Irina P Lushpinskaia, Anton A Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M Pietrek, Patrick Cramer, Lukas S Stelzl, Bojan Zagrovic, Markus Zweckstetter
Journal: Nat Commun
PubMed ID: 37749095
Doi: 10.1038/s41467-023-41633-8
One-step production of fully biotinylated and glycosylated human Fc gamma receptors
Authors: Minhyo Kang, Zening Wang, Xin Ge
Journal: Biotechnol Prog
PubMed ID: 37734055
Doi: 10.1002/btpr.3392
CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia
Authors: Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson
Journal: Nat Struct Mol Biol
PubMed ID: 37679565
Doi: 10.1038/s41594-023-01087-4
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease
Authors: Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep R Atla, Lauren Blankenship, Demonta Coleman, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Journal: biorxiv
PubMed ID: 37808777
Doi: 10.1101/2023.09.29.560163
Vaccination of cattle with the Babesia bovis sexual-stage protein HAP2 abrogates parasite transmission by Rhipicephalus microplus ticks
Authors: Marta G Silva, Reginaldo G Bastos, Jacob M Laughery, Heba F Alzan, Vignesh A Rathinasamy, Brian M Cooke, Carlos E Suarez
Journal: npj Vaccines
PubMed ID: 37758790
Doi: 10.1038/s41541-023-00741-8
Prime editor-mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS-CoV-2 variants
Authors: Wenwen Zhao, Jifang Li, Xiao Wang, Wei Xu, Bao-Qing Gao, Jiangchao Xiang, Yaofeng Hou, Wei Liu, Jing Wu, Qilian Qi, Jia Wei, Xiaoyu Yang, Lu Lu,Li Yang, Jia Chen, Bei Yang
Journal: MedComm.
Doi: 10.1002/mco2.356
A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses
Authors: Sneha Vishwanath, George William Carnell, Matteo Ferrari, Benedikt Asbach, Martina Billmeier, Charlotte George, Maria Suau Sans, Angalee Nadesalingam, Chloe Qingzhou Huang, Minna Paloniemi, Hazel Stewart, Andrew Chan, David Arthur Wells, Patrick Neckermann, David Peterhoff, Sebastian Einhauser, Diego Cantoni, Martin Mayora Neto, Ingo Jordan, Volker Sandig, Paul Tonks, Nigel Temperton, Simon Frost, Katharina Sohr, Maria Teresa Lluesma Ballesteros, Farzad Arbabi, Johannes Geiger, Christian Dohmen, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney
Journal: Nat Biomed Eng
PubMed ID: 37749309
Doi: 10.1038/s41551-023-01094-2

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