Measurement of autoantibodies (AAbs) to tumor associated antigens has been proposed to aid in the early detection of ovarian cancer with high specificity. Here we describe a multiplex approach to evaluate selected peptide epitopes of p53 protein， and propose a novel approach to increase specificity and potentially sensitivity for discrimination between healthy women and women with cancerous masses.
Measurement of autoantibodies (AAbs) to tumor associated antigens has been proposed to aid in the early detection of ovarian cancer with high specificity. Here we describe a multiplex approach to evaluate selected peptide epitopes of p53 protein， and propose a novel approach to increase specificity and potentially sensitivity for discrimination between healthy women and women with cancerous masses.
