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Enhancing CD8+ T cell fatty acid catabolism within a metabolically challenging tumor microenvironment increases the efficacy of melanoma immunotherapy

Cancer Cell, . 2017;

Y.Z., design, experiments, data analyses, writing; R.K., experiments; L.L., metabolomics studies; X.Y.Z., cloning design; A.H. and F.F. assisted Y.Z.; W.G.-D., cell culture; X.W.X., G.K., L.S., W.X., and R.A., human samples collection; G.F., a-PD- Ab; J.R., metabolomics studies; G.Z., M.X., N.S., C.K., and M.H., PDX model, H.E, design, data analyses, and writing.

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Peptide Synthesis	Peptide mTrp-1455-463: TAPDNLGYA Genscript N/A	Get A Quote

摘要

Ying Zhang, Raj Kurupati, Ling Liu, Xiang Yang Zhou, Gao Zhang, Abeer Hudaihed, Flavia Filisio,Wynetta Giles-Davis, Xiaowei Xu, Giorgos C. Karakousis, Lynn M. Schuchter,WeiXu, Ravi Amaravadi, Min Xiao,Norah Sadek, Clemens Krepler, Meenhard Herlyn, Gordon J. Freeman, Joshua D. Rabinowitz