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Combination targeting of 'platelets + fibrin' enhances clot anchorage efficiency of nanoparticles for vascular drug delivery.

Nanoscale. 2020-11; 
Sun M,Miyazawa K,Pendekanti T,Razmi A,Firlar E,Yang S,Shokuhfar T,Li O,Li W,Sen Gupta A
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Peptide Synthesis For platelet binding peptide (PBP) the sequence CGSSSGRGDSPA that binds to activated platelet surface integrin αIIbβ334 was used, and for fibrin binding peptide (FBP), the sequence cyclo-AC-Y(DGI)C(HPr)YGLCYIQGK-Am35 was used. Both peptides were custom synthesized by Genscript (Piscataway, USA). Get A Quote

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